I don’t know of anything in comedy that’s so holy it’d be blasphemous to mess with when done the right way.
I tend to follow Humpty Dumpty’s philosophy with wordage:
"When I use a word," Humpty Dumpty said in rather a scornful tone, "it means just what I choose it to mean — neither more nor less."
"The question is," said Alice, "whether you can make words mean so many different things."
"The question is," said Humpty Dumpty, "which is to be master — that’s all."
And thanks for asking! Keep on Harolding!
(Ask improv-is-easy a question.)